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Comparison of physiology and genome-wide expression in two Nitrosomonas spp. under batch cultivation
DownloadFall 2014
Ammonia oxidizing bacteria (AOB) play a central role in the nitrogen cycle by oxidizing ammonia to nitrite. Nitrosomonas europaea ATCC 19718 has been the single most studied AOB that has contributed to our understanding of chemolithotrophic ammonia oxidation. As a closely related species,...
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Elucidating the basis of poorly understood floral traits associated with pollination biology
DownloadFall 2023
Flowering plants have evolved a stunning array of floral colours, scents, and structures, which act synchronously as cues for pollinators. Comprehensive investigations of the extraordinarily diverse floral features involved in plant-pollinator interactions requires expansion of the comparative...
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Insights into temperature adaptation in the Thermotogae gained through transcriptomics and comparative genomics
DownloadFall 2014
Thermophilic microbes are extremophiles that live at high temperatures. In order to survive and maintain function of their biological molecules, they have a suite of characteristics not found in organisms that grow at moderate temperatures (mesophiles) that range from the cellular to the protein...
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Pollination biology and transcriptomics of Cleomaceae species exhibiting different pollination systems
DownloadFall 2018
Pollinator mediated-selection is responsible for much of the phenotypic diversity exhibited by flowers. Flowering plants or angiosperms that attract a diverse range of pollinators represent a generalist pollination system in which selection is exerted by many different pollinators. However,...
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Fall 2018
Early mammalian development cannot progress without targeted temporal and spatial expression of genes. Changing the accessibility of DNA to transcriptional machinery is one critical way gene expression is controlled. This process, known as chromatin remodeling, is vital for formation of the...
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Transcriptomic analysis of zebrafish prion protein mutants supports conserved cross-species function of the cellular prion protein; and zebrafish as a model for cisplatin induced ototoxicity and transition metals as potential ligands for Tlr4ba and Tlr4bb
DownloadFall 2021
The work presented in this thesis is split between two projects. The first utilises prp1 and prp2 knockout zebrafish to investigate physiological functions of the cellular prion protein (PrPC). The second builds upon the use of zebrafish as a model for hearing loss to confirm a role of toll-like...