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Skip to Search Results- 4Transcriptional regulation
- 1AID
- 1ATHB8
- 1Activation-induced cytidine deaminase
- 1Activation-induced deaminase
- 1Affinity maturation
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Regulation of Pancreatic β-cell Life and Death in the Context of Type 2 Diabetes: Study of the Potential Implication of the Orphan Nuclear Receptor NR4A3/Nor1 and the NZF Transcription Factor ST18.
DownloadFall 2017
Background: The insulin-secreting pancreatic beta-cell plays a central role in the maintenance of glucose homeostasis and in the pathogenesis of both type 1 and type 2 diabetes mellitus. In both cases, production of pro-inflammatory cytokines causes beta-cell apoptosis, which results in the...
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Transcriptional regulation of the zebrafish activation-induced cytidine deaminase (AID) gene
DownloadFall 2012
Activation-induced cytidine deaminase (AID, encoded by Aicda) mediates affinity maturation of immunoglobulin genes. Early studies in mammals indicated that the transcription of Aicda was regulated by a number of transcriptional regulatory regions, including a B-cell specific enhancer in the...
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Transcriptional regulation of two immune genes: teleost activation-induced cytidine deaminase and duck major histocompatibility complex class I
DownloadFall 2015
Differential gene expression allows organisms to develop specialized cell types and promptly respond to foreign pathogens. I) Activation-induced cytidine deaminase (AID/Aicda) is expressed in B-cells to diversify the secondary repertoire and effector functions of antibodies during the processes...
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Spring 2013
The plant vascular system is a network of vascular strands that transport nutrients and signals. Some of these signals control the development of non-vascular tissues surrounding vascular strands; some others coordinate the development of new branches, leaves, and flowers with that of new roots....