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Mechanisms involved in the norepinephrine-mediated protection of synapses from depotentiation
DownloadFall 2016
Norepinephrine (NE) is a key neuromodulator that controls the longevity of synaptic plasticity such as long term potentiation (LTP). Activation of beta-adrenergic receptors (β-ARs) is known to boost persistence of LTP in area CA1 of mouse hippocampal slices. Activity-induced weakening...
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Fall 2009
The computational ability of principal neurons and interneurons in the brain and their ability to work together in concert are thought to underlie higher order cognitive processes such as learning, memory, and attention. Dendrites play a very important role in neuronal information processing...
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Fall 2011
The ability of synapses to undergo lasting changes in synaptic strength is considered the primary cellular mechanism for associative memory formation in the mammalian brain. Synapses in the hippocampus, a brain structure required for new memory genesis, exhibit a remarkable capacity for...