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Structural and Inhibitory Studies of LL-Diaminopimelate Aminotransferase and Investigation of Methods for Small Peptide CrystallizationDownload
The pyridoxal-5'-phosphate (PLP)-dependent enzyme LL-diaminopimelate aminotransferase (LL-DAP-AT) catalyzes a key step in the biosynthesis of L-lysine in plants and Chlamydia. In this thesis, studies of mechanistic and inhibitory aspects of LL-DAP-AT are described. Two LL-DAP-ATs from...