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Fall 2017
Merlin and the ezrin-radixin-moesin (ERM) proteins are key organizers of the cell cortex through linking membrane-associated proteins to the underlying actin cytoskeleton. Merlin and the ERM proteins have been implicated in the maintenance of cell integrity, adhesion, and motility during tissue...
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Fall 2011
Mutations in the NF2 gene lead to the disease Neurofibromatosis Type II which is characterized by the formation of multiple tumours in the central nervous system. The NF2 gene encodes the protein Merlin. Merlin interacts with a number of different proteins and these interactions may be important...
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