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Fall 2023
Alzheimer’s disease (AD) is a common neurodegenerative dementia, and its pathological hallmarks include amyloid-β plaque and neurofibrillary tangle formation in the brain. Genome-wide association studies (GWAS) revealed that a rare single nucleotide polymorphism (SNP) in CD33 is associated with...
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Fall 2024
Across all domains of life, the surface of all cells is coated in a dense array ofcarbohydrates appended to proteins and lipids, collectively referred to as glycans. The interactionbetween glycans and glycan-binding proteins, also known as lectins, are at the interface of nearlyevery biological...