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Fall 2015
Vertebrate eye development is a dynamic process that couples morphogenesis, migration of extraocular periocular mesenchyme (POM) cells to the eye, and retinal patterning along the nasotemporal and dorsoventral (DV) axes. Aberrant patterning during ocular development often results in defects...
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Zic transcription factors regulate retinoic acid metabolism during zebrafish neural development
DownloadSpring 2012
Retinoic acid (RA) has a crucial role in embryonic nervous system development - controlling anterior-posterior patterning, neural differentiation, and cell proliferation. During zebrafish embryogenesis, levels of RA are tightly regulated by the combinatorial action of synthesis and degradation...