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Spring 2020
Renal acclimatization is an important aspect of high-altitude adaption coordinating diuresis, acid-base status, natriuresis, renal hemodynamics and kidney filtration. Renal blood flow, glomerular filtration rate, active renin, plasma aldosterone concentration, NT pro-brain natriuretic peptide...
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Fall 2009
Human cells possess multiple nucleoside transporters (NTs) that belong to either the human equilibrative or concentrative NT (hENT: hENT1/2/3/4; hCNT: CNT1/2/3) families. In the kidney, coupling of apical hCNT3 activities to basolateral hENT1/2 activities is hypothesized to mediate renal...
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Splenic neurohormonal modulation of renal and mesenteric hemodynamics in portal hypertension
DownloadFall 2009
Persistent elevation of portal venous pressure (portal hypertension- PH), is linked to chronic liver disease and invariably leads to multi-organ circulatory complications. Hallmarks of PH are renal dysfunction and a characteristic hemodynamic profile (hyperdynamic circulation), which...
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Fall 2018
Chloride intracellular channel (CLIC) proteins comprise six members CLIC1–CLIC6 in mammals and mediate functions not fully known. Their founding member was isolated from bovine kidney using the chloride channel inhibitor indanyloxyacetic acid-94, so CLICs were assumed to be typical anion...