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Skip to Search Results- 2Prions
- 1Antibody fragments
- 1Chronic wasting disease
- 1Immunogold Labelling
- 1Molecular dynamics simulations
- 1PrPSc-specific fluobody
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Spring 2023
Prion diseases are rare, inexorably progressive, and fatal neurodegenerative disorders, with no therapy other than palliation. The key event in the pathogenesis of prion diseases is the conformational conversion of the cell-surface glycoprotein (PrPC), from a predominantly α-helical structure...
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Fall 2023
Prion diseases are a group of deadly neurological disorders caused by the abnormal folding of the prion protein into an infectious form known as PrPSc. Chronic wasting disease is a prion disease affecting cervids such as deer, elk, moose, and reindeer. Despite ongoing efforts to understand prion...