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Fall 2024
Viral diseases are a constant threat that have profound impact on global health, economics and societies. Understanding virus-host interactions is key for advancing our knowledge of viral replication and pathogenesis, and thus for the development of effective antiviral strategies to better...
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Fall 2022
Post-translational modifications (PTMs) regulate a variety of normal cellular processes, many of which are conserved across eukaryotes and prokaryotes. One PTM, protein glycosylation with the reversible modification of O-GlcNAc, is well studied in eukaryotes. However, evidence for its existence...
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Fall 2017
Protein prenylation is the post-translational addition of isoprenoid lipid moieties to proteins, which regulates their subcellular localization and function. Farnesyl or geranylgeranyl isoprenoids are covalently linked to cysteines residues in a C-terminal prenylation recognition sequence in...