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Evaluating the Role of Bacterial Lipopolysaccharide on Etiology and Pathogenesis of Transmissible Spongiform Encephalopathies
DownloadFall 2014
Transmissible spongiform encephalopathies (TSEs) or otherwise known as prion diseases are a class of fatal neurodegenerative diseases related to irreversible brain damage. Presently, there is no effective treatment or preventive strategy for this disease because the etiology and biological...
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Investigating the 197Au-31P spin-spin coupling interactions in gold-phosphine halides using solid-state nuclear magnetic resonance, spectral simulations, and quantum chemistry computations
DownloadSpring 2011
Phosphorus-31 nuclear magnetic resonance spectroscopy with magic angle spinning was used to characterize 197Au-31P spin-spin coupling interactions in solid gold-phosphine halides and the spectra have been analyzed using perturbation theory. The 197Au nucleus has a natural abundance of 100%, a...
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Fall 2012
Thuricin CD, a two-component bacteriocin produced by Bacillus thuringiensis DPC 6431, exhibits potent activity against the hospital superbug Clostridium difficile ribotype O27. The two peptides (Trn-α and Trn-β) that constitute thuricin CD operate synergistically to kill sensitive bacteria at...