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Skip to Search Results- 2NLRP3 inflammasome
- 112,13-DiHOME
- 1Cardiac inflammation
- 1Cytochrome P450 epoxygenase
- 1Epoxide hydrolase
- 1Epoxylipids
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Effects of Genetic Deletion of Soluble Epoxide Hydrolase on Cardiac Function and Inflammation in Acute Lipopolysaccharide Injury
DownloadSpring 2022
Acute inflammatory syndromes, such as endotoxemia, elicit detrimental multi-organ responses resulting in cardiac dysfunction often leading to death. Emerging evidence suggests epoxylipids can exert cardioprotective effects by modulating the NOD-like receptor family pyrin domain containing 3...
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Fall 2023
12,13-dihydroxy-9z-octadecenoic acid (12,13-DiHOME) is a linoleic acid-derived cardiac metabolite produced in endotoxin-induced cardiomyopathy, correlating with myocardial dysfunction, inflammation, and mitochondrial damage. The contribution of 12,13-DiHOME to inflammation in the heart is...