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Characterization of Galectin-9+ and TIGIT+ Natural Killer Cells in Human Immunodeficiency Virus-1 Infected Individuals
DownloadFall 2019
NK cells play an integral role in mediating immune responses to viral infections; however, their function is compromised during chronic diseases such as HIV-1, partly due to an increase in expression of inhibitory receptors. Thus, one of the reasons for the reduced immune responses elicited by NK...
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Fall 2015
Natural killer (NK) cells in the mouse and rat rely on homodimeric Ly49 receptors to detect virally infected or transformed cells. The identification of altered cells requires the engagement of Ly49 receptors with MHC class I molecules. The engagement requires contact at three specific sites...