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Engineering Stable Bacteriophage Dosage Forms Active Against Antibiotic-Resistant Bacteria for Respiratory Delivery and Food Safety Applications
DownloadFall 2019
The topic of this thesis is the engineering of stable bacteriophage dosage forms that are active against antibiotic-resistant bacteria for applications in respiratory delivery and food safety. Experimental methods and theoretical models are developed to test and understand the effects that...
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Synthesis of Furanose Sugar Nucleotides from Mycobacterium tuberculosis and Campylobacter jejuni
DownloadSpring 2014
Five-membered ring furanose sugars, though absent in mammals, have been found in the cell walls of pathogenic bacteria such as Mycobacterium tuberculosis and Campylobacter jejuni. Because these sugars are only found in microorganisms, it has been proposed that inhibiting the enzymes these...