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A path towards better cancer drugs: Modeling interactions between antimitotic agents and tubulin
DownloadFall 2015
Antimitotic agents, a class of cancer chemotherapies, target the tubulin protein in microtubules to suppress microtubule dynamics and affect the segregation of chromosomes during cell division. A variety of antimitotic agents are known, which range in status from clinically-approved agents to...
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Fall 2015
Microtubules are cellular structures that are crucial to many cellular functions including maintenance of cell shape, vesicular transport, and cell division. The dynamic instability of microtubules is the basic feature which enables them to do their cellular functions. Their pivotal role in cell...