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Skip to Search Results- 3Matrix metalloproteinase-2
- 1Bovine serum albumin
- 1Calcium sensitizer
- 1Calpain inhibitors
- 1Cardiac troponin complex
- 1Cell death
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Spring 2010
Coacervation is a mild process for developing protein NPs. Bovine serum albumin (BSA) NPs formed via this technique were stabilized using poly-L-Lysine (PLL); short interfering ribonucleic acid (siRNA) was used as a model drug for encapsulation. Specific and non-specific degradation of these...
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Mutations, post-translational modifications, and small molecule binding to the cardiac troponin complex alter cardiac contractile function
DownloadFall 2021
Ischemic heart disease is the leading cause of death worldwide. It can lead to acute myocardial infarction, commonly known as a “heart attack”, in which heart muscle dies due to disruption of its oxygen and blood supply. Even if patients survive a heart attack and receive the best medical therapy...
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Fall 2012
Despite originally being described as a secreted protease, matrix metalloproteinase‐2 (MMP‐2) was recently revealed to have targets within cardiomyocytes. The biological mechanism(s) that describes the intracellular localization of MMP‐2 is unknown and is thus the subject of this thesis....