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Fall 2015
In rodents, Ly49s are prominent natural killer (NK) cell receptors that interact with peptide-bound class I major histocompatibility complex (MHC-I). This association generally induces inhibitory signals when MHC-I presents self-peptides, thus blocking NK cell activation against healthy cells....
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Investigating the differential effects of LILRB1 natural variants on interaction with MHC-I and UL18
DownloadFall 2022
The Leukocyte immunoglobulin-like receptor B1 (LILRB1) is widely expressed throughout human immune cells of lymphoid and myeloid origins. It is also associated with viral infection, autoimmune diseases and cancer. LILRB1 regulates immune responses through broad interaction with major...