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- 1BRCA1 BRCT
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- 1CK2-mediated Phosphorylation
- 1Co-expression of Human Histone Oligomers
- 1Co-expression of Nucleosome Core Particle
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Development of Systems for Expression, Purification, and CK2-Mediated Phosphorylation of the Histone Oligomers
DownloadFall 2018
It is of extreme importance to investigate the DNA repair pathways that will lead to a better understanding to develop cancer treatments since the primary cause of cancer is the inability of the cell to restore the damaged DNA. Upon DNA damage, the histone tails of the nucleosomes near the DNA...
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Spring 2018
The BRCT domain family is a group of proteins that is primarily involved in the regulation of DNA replication, cell cycle checkpoint activation, DNA damage repair, and many other DNA damage responses (DDR). Mutations in BRCT proteins often result in genomic instability, one of the leading sources...