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Spring 2012
Inhalation of benzene is associated with increased risk of leukemia. Edmonton Indoor Air Quality Study (EIAQS) investigated what factors were related to higher or lower levels of benzene in Edmonton homes. Factors examined were: season (winter, summer), environment (indoor, outdoor), traffic...
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Myeloperoxidase-mediated bio-activation of NSAIDs in leukemia cells: Potential selective cytotoxicity
DownloadFall 2019
Several lines of evidence have pointed to the potential benefit of anti-inflammatory drugs (NSAIDs) in cancer therapy due to the well-established correlation between cancer and chronic inflammation. Acute myeloid leukemia (AML) cells overexpress myeloperoxidase (MPO), which has been studied for...
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Spring 2017
BCR-ABL fusion oncogene is the main driver mutation of Chronic Myeloid Leukemia (CML) that controls initiation, maintenance and progression to more aggressive stages of the disease. Current therapies with tyrosine kinase inhibitors in CML involve certain limitations, such as drug resistance and...