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Spring 2016
Peptides have a host of beneficial physiological effects and are often considered for therapeutic application to treat disease. However, poor bioavailabilities, problems with administration, sensitivity to environmental factors, and susceptibility to proteases limit them. The work presented in...
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Synthesis and biological evaluation of the lantibiotic peptide lactocin S and its analogues
DownloadSpring 2012
Lantibiotics (lanthionine containing antibiotics) are highly post-translationally modified peptides used by bacteria as a form of chemical warfare. In light of the challenges faced today in the field of antibacterial therapy, these potent natural products are useful lead compounds for the...