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Implications of genetic diversity on expression of LILRB1 in Natural Killer cells and susceptibility to HCMV infection in transplant patients
DownloadFall 2016
Leukocyte Ig-like Receptor 1 (LILRB1) is an inhibitory receptor expressed on a number of immune cells. The expression profile on NK cells is variable between people, with a range of 25-80% of NK cells expressing LILRB1. We previously uncovered a correlation between genotype within the 5’ end of...
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Fall 2013
Natural killer (NK) cells are innate immune lymphocytes that provide protection against virus infection and transformation. The cytolytic activity of NK cells is controlled by the signaling of receptors that stimulate or inhibit activation. One such inhibitory receptor expressed on human NK cells...