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Skip to Search Results- 1Chan, Catherine B.
- 1Holloway, Graham P.
- 1MacDonald, Tara
- 1Perry, Christopher G.
- 1Proctor, Spencer D.
- 1Shi, Danni
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 1Toolkit for Grant Success
- 1Toolkit for Grant Success/Successful Grants (Toolkit for Grant Success)
- 1Graduate and Postdoctoral Studies (GPS), Faculty of
- 1Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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2018-10-16
SSHRC NFRF-E awarded 2019: With the requested funding, I will apply my expertise in T cells and metabolism to identify new potential metabolic drugs that can enhance immune function. We hypothesize that a Insulin-Resistance (IR)-related immune and metabolic defect contributes to increased risk of...
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2012
Wan, Zhongxiao, MacDonald, Tara, Wright, David C., Holloway, Graham P., Chan, Catherine B., Perry, Christopher G.
Background Adipose tissue mitochondria have been implicated as key mediators of systemic metabolism. We have shown that IL-6 activates AMPK, a mediator of mitochondrial biogenesis, in adipose tissue; however, IL-6−/− mice fed a high fat diet have been reported to develop insulin resistance. These...
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Insulin and testosterone are associated with elevated intestinal secretion of lipids and lipoproteins in a rodent model of the metabolic and polycystic ovary syndrome
Download2014
Wang, Ye, Shi, Danni, Proctor, Spencer D., Vine, Donna F.
The metabolic syndrome is highly associated with the incidence of Polycystic Ovary Syndrome (PCOS). The metabolic aberrations of insulin resistance and hyperandrogenemia have been proposed to contribute to the development of dyslipidemia and increased Cardiovascular Disease (CVD) risk in PCOS....
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The metabolic basis of cell identity in the pulmonary arteries and the right ventricle in pulmonary arterial hypertension
DownloadFall 2023
Pulmonary arterial hypertension (PAH) is an incurable disease characterized by profound pulmonary vascular remodeling, including the development of plexogenic lesions (which is the hallmark of PAH) that results in lumen obliteration, raising the pulmonary vascular resistance (PVR) and the right...