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Fall 2010
With asphyxia, newborns may suffer cardiogenic shock with myocardial dysfunction and dysregulation of vasomotor tone resulting in multiorgan dysfunction. Vasoactive medications are often administered with limited evidence directing clinicians regarding the use of high-dose monotherapy with...
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Fall 2011
The pumping of the heart is controlled at the molecular level by the calcium dependent interaction between troponin C (cTnC) and troponin I (cTnI). The central role this protein-protein interaction plays in the muscle contraction cascade makes it a prime target for the development of drugs for...