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Development of Novel Models to Study Sub and Post Cellular Uptake of Drugs Following Oral Administration
DownloadFall 2024
Given the numerous benefits of oral administration, this thesis investigates two key phenomena influencing the pharmacokinetics and pharmacodynamics of orally administered active pharmaceutical ingredients (APIs): lysosomal trapping and intestinal lymphatic uptake via chylomicrons, with a...
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Spring 2018
The inertial filtration properties of neonatal infant nasal airways are the focus of this thesis. Nasal replicas based on computed tomography (CT) scan images of seven infants between the ages of 5 and 79 days were created using three-dimensional printing. Deposition of inertial sized aerosol...