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Diabetes-prone BioBreeding rats do not have a normal immune response when weaned to a diet containing fermentable fibre
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Bell, Rhonda C., Field, Catherine J., Stillie, RoseMarie
Diet is known to modulate the development of diabetes in diabetes-prone BioBreeding (BBdp) rats. The objective of the present study was to determine the effect of fermentable fibre (FF) on immune function in BBdp and diabetes-resistant BioBreeding (BBdr) rats after weaning. Weanling BBdp...
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2018-10-16
SSHRC NFRF-E awarded 2019: With the requested funding, I will apply my expertise in T cells and metabolism to identify new potential metabolic drugs that can enhance immune function. We hypothesize that a Insulin-Resistance (IR)-related immune and metabolic defect contributes to increased risk of...