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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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Effect of Consuming Dairy Fats on Obesity-Related Cardiometabolic Perturbations and Immune Function in Low Birthweight Swine
DownloadSpring 2023
Although dairy intake has been shown to have a neutral or some beneficial effect on major cardiometabolic risk factors, the impact of dairy, and especially dairy fat, on immune function remains to be investigated. To understand the effect of consuming dairy fat on cardiometabolic risk factors and...
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Fall 2024
Multiple sclerosis (MS) is an autoimmune disease that is characterized by demyelination of central nervous system axons. Symptoms of MS are highly heterogenous, although some, such as motor deficits and chronic pain, are very common in those with the disease. Defined by the International...
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Fall 2009
The renin-angiotensin system (RAS) has been implicated in vascular inflammation and atherosclerosis. Angiotensin II via the ATR1 can activate monocytes to produce inflammatory factors and increase adhesion. ATR1 expression is partly regulated by alternate splicing of the ATR1 gene. The RAS may...