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Characterizing the Efficacy of Ice Recrystallization Inhibitors as a Novel Cryoprotectant for Lung Cryopreservation
DownloadFall 2020
Although lung transplant remains the only option for patients suffering from end-stage lung disease, donor lung supply is currently insufficient to meet demand. While many lungs become available for transplant, most are discarded due to failure to meet physiologic or compatibility criteria. Many...
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The Efficacy of Using Small Molecule Ice Recrystallization Inhibitors to Enable the Frozen Storage of Livers
DownloadFall 2020
The limited storage times afforded by hypothermic preservation at 0 °C to 4 °C imposes several logistic constraints on the organ transplant network. In the case of livers, two-thirds of wait listed patients do not receive transplants in Canada, which is partially attributed to the 12 h storage...