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Helicobacter pylori infection in Arctic Indigenous communities: assessing the validity of infection status measures and estimating the effect of bacterial load on gastritis severity
DownloadSpring 2023
Helicobacter pylori (Hp) causes chronic inflammation of the stomach lining, also known as gastritis, in nearly all people with a persistent infection. Chronic inflammation of the stomach lining can lead to atrophy of stomach glands, a condition known as atrophic gastritis, believed to be the...
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Whose burden? A comprehensive approach to describing burden of disease by synthesizing evidence from diverse perspectives
DownloadFall 2018
Epidemiologists tasked with addressing public concerns about a specific health issue and developing effective public health strategies aimed at reducing related health risks must begin by describing the extent of the health threat in the target population. Typical approaches use quantitative...
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Fall 2020
Helicobacter pylori (Hp) infection has an elevated prevalence in northern Indigenous communities in Canada. This thesis investigates social inequities in the Hp-associated disease burden within Indigenous communities in the Northwest Territories and Yukon. I examined how deprivation indicators...
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Environmental Exposures, Helicobacter pylori Infection and Gastritis in Canadian Arctic Communities
DownloadSpring 2013
The role of environmental exposures in the acquisition of H.pylori and related disease is not yet understood. This analysis examined two hypotheses regarding how environmental exposures may affect digestive health in northern Canada. First, environmental sources of biological contamination may...