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Fall 2017
Heart failure (HF) is a common, costly, disabling and deadly syndrome. It places a considerable burden on Canadian society and on patients, their families, and the health care system. Self-care behaviors are essential to effective HF management. Adherence to some self-care recommendations,...
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Fall 2022
Background The discovery of angiotensin-converting enzyme 2 (ACE2) introduced an alternative protective arm of the renin-angiotensin system (RAS), the ACE2/Angiotensin 1-7 (Ang 1-7)/Mas receptor axis, to counterbalance the more renowned pathogenic angiotensin-converting enzyme (ACE)/Angiotensin...
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The Role of Subterminal Hydroxyeicosatetraenoic Acids in the Pathogenesis of Cardiac Hypertrophy
DownloadFall 2021
Cardiac hypertrophy is a complex condition which is characterized by increased mass of the heart muscle. If untreated, cardiac hypertrophy can ultimately lead to heart failure (HF), arrhythmia and sudden death. Accumulating evidence suggest that pathological cardiac hypertrophy is strongly...
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Understanding Heart Failure in Patients with Dilated Cardiomyopathy: A Direct Tissue Analysis from Explanted Human Hearts
DownloadFall 2022
Background Chronic heart failure (HF) remains a rising global epidemic that affects both adults and children population. The causes of HF are heterogeneous, and syndromes are often complicated by concomitant disorders such as iron deficiency (ID) and diabetes. Comorbidities not only complicate...
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Using Intersectionality Theory and Critical Realism for Exploring Heart Failure Telehealth Interventions for Vulnerable Patient Populations: A Scoping Review, Intersectionality-based Analysis, and A Rapid Realist Review
DownloadFall 2022
Background: Heart Failure (HF) is at epidemic levels among older adults, globally. Heart Failure Disease Management Interventions (HFDMIs) enhance self-care and quality of life as well as reduce hospital readmissions, through patient education and follow up, effective treatment, psychosocial...