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Characterization of Galectin-9+ and TIGIT+ Natural Killer Cells in Human Immunodeficiency Virus-1 Infected Individuals
DownloadFall 2019
NK cells play an integral role in mediating immune responses to viral infections; however, their function is compromised during chronic diseases such as HIV-1, partly due to an increase in expression of inhibitory receptors. Thus, one of the reasons for the reduced immune responses elicited by NK...
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Elucidating how HIV-1 infection influences CD4, CD8 and regulatory T cell phenotype and function
DownloadFall 2021
Human Immunodeficiency Virus (HIV) infection is still a global health issue. Although the advent of highly active antiretroviral therapies (HAART) to suppress viral replication has transformed HIV infection from a lethal disease to a chronic and manageable infection, it does not cure HIV. CD8 T...