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Spring 2015
Advance in biotechnologies has enabled genome-wide association studies (GWAS) that scan the entire human genome for understanding genetic contributions to the risk of a certain disease as well as to variation in treatment efficacy and side effects. In GWAS, the association between each...
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Identification of Shared and Distinct Gene-disease Associations Among Multiple Related Diseases and Multiple Subtypes of a Disease
DownloadFall 2013
Genome-wide association study (GWAS) is an approach with high-throughput genotyping to uncover genetic susceptibilities of complex diseases. However, the genetic susceptibilities discovered usually carry very small risk increments. Additionally, the current approach to assess whether these...