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- 1Cloning
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- 1Aguzzi, Adriano
- 1Bellon, Anne
- 1Garen, Graciela
- 1Hafner-Bratkovič, Iva
- 1Hornemann, Simone
- 1James, Michael N. G.
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The POM monoclonals: A comprehensive set of antibodies to non-overlapping prion protein epitopes
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Hafner-Bratkovič, Iva, Aguzzi, Adriano, Vey, Martin, Polymenidou, Magdalini, Yajima, Bill , James, Michael N. G., Jerala, Roman, Moos, Rita, Scott, Mike, Shi, Yong-zhong, Wuthrich, Kurt, Garen, Graciela, Sigurdson, Christina, Hornemann, Simone, Bellon, Anne, Kav, Nat
PrPSc, a misfolded and aggregated form of the cellular prion protein PrPC, is the only defined constituent of the transmissible agent causing prion diseases. Expression of PrPC in the host organism is necessary for prion replication and for prion neurotoxicity. Understanding prion diseases...