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Development and optimization of a high through-put screening methodology for rapid dynamic range improvement of FRET-based biosensors
DownloadSpring 2012
Abdel Latif Ibraheem, Ahmed Abdel Mohsen
Fluorescent protein (FP)-based biosensors based on the principle of intramolecular Förster resonance energy transfer (FRET) enable the visualization of a variety of biochemical events in living cells. The sensitivity of such biosensors is proportional to the change in ratiometric emission, and so...
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