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Downregulation of the FOXM1 transcription factor by dual nitric oxide-/ hydrogen sulfide-donors: preliminary structure-activity relationshipsDownload
In recent decades, the Forkhead Box (FOX) family of transcription factors (e.g. FOXM1) has attracted the attention of the scientific community due to its significant role in cancer initiation and progression. Furthermore, the abnormal or deregulated expression of FOXM1 has been associated with...
Preliminary validation of a computer-based approach to find new lead molecules targeting the oncogenic Forkhead box M1 transcription factorDownload
The upregulation of the forkhead box M1 (FOXM1) transcription factor is directly correlated with cancer initiation, invasion, and drug resistance. Because the overexpression of FOXM1 is considered an important factor in carcinogenesis, this protein could be a relevant drug target in cancer...