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Function and Regulation of Equilibrative Nucleobase Transporter 1 in Acute Lymphoblastic Leukemia
DownloadFall 2024
Background: 6-Mercaptopurine (6-MP) is a purine nucleobase analog used for the treatment of acute lymphoblastic leukemia (ALL), inflammatory bowel disease, and other disorders. 6-MP is primarily used in ALL, the most common childhood cancer. Enzymes involved in 6-MP metabolism have been shown to...
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