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Skip to Search Results- 2Drug discovery
- 1A162H
- 1Cardiac troponin
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- 1Muscle contraction
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Fall 2022
Functionalized piperidine rings are frequently found in a variety of alkaloids and pharmaceuticals attesting to the importance of this class of heterocycles in drug discovery. According to recent data, the piperidine ring is the most abundant heterocycle found in FDA approved drugs. Thus, gaining...
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Molecular Mechanisms Underlying the Enhancement of Cardiac Contraction by Modifications of Troponin
DownloadFall 2015
A fine balance between contraction and relaxation is crucial for the heart to function properly. But often the heart cannot contract with enough force to meet the demands of the body. This condition, called systolic heart failure, is the leading cause of death in the modern society. A common...