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Fall 2021
Facioscapulohumeral muscular dystrophy (FSHD) and Duchenne muscular dystrophy (DMD) are two of the most commonly inherited muscular disorders in the world. There is currently no cure for both of them. Antisense oligonucleotides (AOs) are short, synthetic, single-stranded nucleic acids that...
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Spring 2016
Facioscapulohumeral muscular dystrophy (FSHD) is a neuromuscular disorder characterized by early involvement of muscle weakness. FSHD is most commonly caused by a deletion of a subset of D4Z4 macrosatellite repeats at the locus located on chromosome 4q35. Within each D4Z4 repeat unit is a double...