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Fall 2015
DNA is a detailed layout of instructions for cellular function. The integrity of human DNA is constantly challenged by a barrage of exogenous and endogenous sources. A regime of genome stability maintenance has evolved to repair the many different types of DNA damage. A form of communication...
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Fall 2010
Asf1 is a conserved H3/H4 histone chaperone with multiple functions in chromatin modulation. Using budding yeast as a model, we identify new pathways of Asf1 function, and expand current knowledge regarding the known roles of Asf1. First, we uncover novel genetic interactions between ASF1 and...