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Skip to Search Results- 5Field, Catherine J.
- 4Proctor, Spencer D.
- 3Ametaj, Burim N.
- 3Chakrabarti, Subhadeep
- 3Willing, Benjamin P.
- 3Wu, Jianping
- 59Graduate and Postdoctoral Studies (GPS), Faculty of
- 59Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 24Agricultural, Food and Nutritional Science, Department of
- 24Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Roy Berg Kinsella Research Ranch
- 3Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
- 8Department of Medicine
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- 2Barreda, Daniel (Biological Sciences)
- 2Foley, Edan (Medical Microbiology and Immunology)
- 2Jamali, Fakhreddin (Faculty of Pharmacy and Pharmaceutical Sciences)
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- 1Ametaj, Burim N. (Agricultural, Food and Nutritional Science)
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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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Chronic Heart Failure: The Roles of the Tumor Necrosis Factor-Alpha Axis and Left-Atrial Structural and Functional Remodeling
DownloadFall 2014
Heart failure (HF) is a global epidemic, with a substantial burden on healthcare systems. Effective therapies have emerged for patients suffering from HF with reduced ejection fraction (HFREF), but not for those with preserved ejection fraction (HFPEF). Recently, systemic inflammation, driven by...
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Clinical impact of submicroscopic malaria on delivery outcomes and the role of VAR2CSA antibodies in pregnant women from Colombia
DownloadFall 2018
Malaria caused by the genus Plasmodium (P.) is one of the oldest and most important parasitic infections globally. Pregnant women are at an increased risk for malaria, where the disease poses a significant risk to both maternal and child health. Better diagnosis of malaria can have an immediate...
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Commensal bacteria and expression of two major intestinal chemokines, TECK/CCL25 and MEC/CCL28, and their receptors
Download2007
Gerdts, Volker, Meurens, Francois, Willing, Benjamin P., Berri, Mustapha, Siggers, Richard H., Van Kessel, Andrew G., Salmon, Henri
Background CCL25/TECK and CCL28/MEC are CC chemokines primarily expressed in thymic dendritic cells and mucosal epithelial cells. Their receptors, CCR9 and CCR10, are mainly expressed on T and B lymphocytes. In human, mouse, pig and sheep CCL25 and CCL28 play an important role in the segregation...
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Comparative isolation of bacteria from inflamed sites to identify inflammation-tailored bacteria
DownloadSpring 2021
Microbial culture collections are fundamental to microbiology research. However, with the advent of next generation sequencing research, the generation and maintenance of comprehensive culture collections has become deprioritized. As such a need exists for the improved isolation of diverse...
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Comparative transcriptomic analysis of rectal tissue from beef steers revealed reduced host immunity in Escherichia coli O157:H7 super-shedders
Download2016-03-09
McAllister, Tim A., Wang, Ou, Plastow, Graham, Stanford, Kim, Liang, Guanxiang, Guan, Le L., Selinger, Brent
Super-shedder cattle are a major disseminator of E. coli O157:H7 into the environment, and the terminal rectum has been proposed as the primary E. coli O157:H7 colonization site. This study aimed to identify host factors that are associated with the super-shedding process by comparing...
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Comparative variation within the genome of Campylobacter jejuni NCTC 11168 in human and murine hosts
Download2014
Selinger, L. Brent, Taboada, Eduardo N., Uwiera, Richard R. E., Abbott, D. Wade, Inglis, G. Douglas, Thomas, Dallas K., Lone, Abdul G.
Campylobacteriosis incited by C. jejuni is a significant enteric disease of human beings. A person working with two reference strains of C. jejuni National Collection of Type Cultures (NCTC) 11168 developed symptoms of severe enteritis including bloody diarrhea. The worker was determined to be...
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Contributions of Bim and Nur77 to multiple mechanisms of T cell tolerance following high affinity antigen encounter
DownloadSpring 2015
Prevention of autoimmune disease requires the elimination or inactivation of T cells that are highly reactive to self-peptides. During T cell development in the thymus, self-reactive thymocytes undergo negative selection upon receiving a high affinity T cell receptor (TCR) signal following...
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Development of Polymeric Micelles for Site Specific Delivery of Nonsteroidal Anti-Inflammatory Drugs: Effect on the Cardiovascular Risk in an Experimental Model of Arthritis
DownloadFall 2019
Non-steroidal anti-inflammatory drugs (NSAIDs), which inhibit cyclooxygenase (COX) enzymes, are among the most widely used medications worldwide with proven efficacy in controlling inflammation and pain associated various disease conditions. The chronic systemic use of most NSAIDs, however, is...