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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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The role of Receptor Interacting Serine/Threonine Kinase 2 (RIPK2) in inflammatory breast cancer (IBC)
DownloadFall 2022
Inflammatory breast cancer (IBC) is a rare but aggressive type of breast cancer characterized by early and rapid metastasis leading to poor clinical outcomes. The tumor microenvironment (TME), including immune cells, fibroblasts and endothelial cells, has emerged as a major regulator of IBC...