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A comprehensive investigation of cycloalkenyl-alkyne coupling reactions mediated by cobalt(III) templates is presented. The in situ derived cationic η3-cyclohexenyl complexes of cobalt(III) react with some terminal alkynes to afford either η1,η4-bicyclo[4.3.1]decadienyl or...
A new method for the preparation of seven-membered carbocycles via cobalt-mediated [5+2] cycloaddition methodology is presented. We have demonstrated that Cp*Co(η5-pentadienyl)+ systems undergo cycloaddition reactions with alkynes in a diastereocontrolled and high-yielding process. When...
The five-membered carbocycle is a structural motif found in a plethora of natural products and bioactive compounds. The Nazarov reaction has emerged as an effective method to synthesize cyclopentenones and acts as a tool for adding structural complexity to molecular frameworks. This dissertation...