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Skip to Search Results- 1Dr. Dion R. Brocks, Faculty of Pharmacy and Pharmaceutical Sciences
- 1Dr. Scot Simpson (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Eurich, Dean (Public Health)
- 1Necyk, Candace (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Simpson, Scot (Pharmacy)
- 1Simpson, Scot H. (Faculty of Pharmacy and Pharmaceutical Sciences)
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Exploring the Relationship Between Depression and Adherence in Individuals with Type 2 Diabetes
DownloadFall 2020
Background: Depression is a well-known risk factor for poor medication adherence in individuals with diabetes; however, this association is based on cross-sectional and cohort studies measuring adherence after depression is diagnosed. Symptoms of depression often progress before medical...
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Mechanisms of Pharmacists Interventions on Medication Management and Adherence in Patients with Type 2 Diabetes
DownloadSpring 2014
Optimal management of type 2 diabetes requires a collaborative, team-based approach; however, the role of pharmacists on these teams has not been well-defined. In the first study of this thesis, a systematic review examined components of pharmacist interventions to improve adherence to oral...
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Myeloperoxidase-mediated bio-activation of NSAIDs in leukemia cells: Potential selective cytotoxicity
DownloadFall 2019
Several lines of evidence have pointed to the potential benefit of anti-inflammatory drugs (NSAIDs) in cancer therapy due to the well-established correlation between cancer and chronic inflammation. Acute myeloid leukemia (AML) cells overexpress myeloperoxidase (MPO), which has been studied for...
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Fall 2016
Seniors requiring advanced care and supports are often residing in residential care facilities (RCF). Although, up to 33% of the residents are living with known diabetes, administrators and clinicians are faced with two important questions: 1) what is the prevalence of undetected diabetes; and,...
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The effect of oral lipids and lipoproteins on the biodistribution, metabolism and electrocardiographic side-effects of halofantrine
DownloadSpring 2011
In the past, hyperlipidemia (HL) has been shown to affect the pharmacokinetic and pharmacodynamic properties of lipophilic drugs extensively bound to lipoproteins, including halofantrine (HF). The present thesis examined the effect of HL on the biodistribution, metabolism and electrocardiographic...