Search
Skip to Search Results-
Computational identification of residues that modulate voltage sensitivity of voltage-gated potassium channels
Download2005
Background: Studies of the structure-function relationship in proteins for which no 3D structure is available are often based on inspection of multiple sequence alignments. Many functionally important residues of proteins can be identified because they are conserved during evolution. However,...
-
2006
Cooper, W., Hogg, M., Reha-Krantz, L., Wallace, S.S.
The kinetics of forming a proper Watson–Crick base pair as well incorporating bases opposite furan, an abasic site analog, have been well characterized for the B Family replicative DNA polymerase from bacteriophage T4. Structural studies of these reactions, however, have only been performed with...
-
Orally Administered P22 Phage Tailspike Protein Reduces Salmonella Colonization in Chickens: Prospects of a Novel Therapy against Bacterial Infections
Download2010
Henry, M., Tanha, J., Foss, M., Ryan, S., Masotti, M., Coleman, R., Hanifi-Moghaddam, P., MacKenzie, R., Waseh, S., Szymanski, C.M.
One of the major causes of morbidity and mortality in man and economically important animals is bacterial infections of the gastrointestinal (GI) tract. The emergence of difficult-to-treat infections, primarily caused by antibiotic resistant bacteria, demands for alternatives to antibiotic...