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- 2Cholesterol
- 1APP and Aβ metabolism
- 1Alzheimer's disease
- 1Arachidonic acid
- 1Electrophysiology
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Spring 2013
Alzheimer’s disease (AD) is a complex neurodegenerative disorder believed to be triggered by the accumulation of β-amyloid (Aβ)-related peptides derived from the proteolytic processing of amyloid precursor protein (APP). Research over the last two decades has shown that alterations in the levels...
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Influence of lipids (arachidonic acid and cholesterol) on calcium signalling in rodent pancreatic beta cells
DownloadFall 2010
Ca2+ is an important mediator of stimulus-secretion coupling in beta cells of the pancreatic islets, which secrete insulin in response to elevation in plasma glucose concentration. I studied the actions of two lipids, arachidonic acid (AA) and cholesterol, on enzymatically-dissociated single...
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