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Insights into the Role of Phosphatidylethanolamine N-methyltransferase and the PC:PE Ratio in Liver Function
DownloadSpring 2019
PEMT is quantitatively important in the liver and is responsible for approximately 30% of hepatic PC synthesis, with the remaining 70% synthesized by the CDP-choline pathway. HFD-fed Pemt-/- mice and LPcyt1a-/- mice both develop NAFLD associated with reduced VLDL secretion and a reduced hepatic...
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