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- 14Graduate Studies and Research, Faculty of
- 14Graduate Studies and Research, Faculty of/Theses and Dissertations
- 7Rehabilitation Medicine, Faculty of
- 3Rehabilitation Medicine, Faculty of/Speech Pathology and Audiology
- 3Rehabilitation Medicine, Faculty of/General Rehabilitation Medicine
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- 5Medical Sciences-Paediatrics
- 3Faculty of Rehabilitation Medicine
- 2Department of Communication Sciences and Disorders
- 1Department of Biomedical Engineering
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- 1Department of Speech Pathology and Audiology
Alterations in Neural Connectivity following Placental Insufficiency, its Role in Neurodevelopmental Disabilities, and the Neuropreventive Effects of Broccoli Sprout Supplementation: A Potential Therapeutic InterventionDownload
Background Intrauterine growth restriction (IUGR) as a result of suboptimal in utero environments can cause perinatal brain injury and ultimately lead to neurodevelopmental disorders (NDD). In the developed world placental insufficiency (PI) is the leading cause of IUGR. This antepartum insult...
Bilateral Uterine Artery Ligation in Rats cultivates Long Term Neurological Deficits reminiscent of Human Cerebral Palsy: A model for Therapeutic Intervention.Download
Introduction Cerebral Palsy (CP) is a ubiquitous term used to describe a group of permanent, non-progressive disorders of movement, posture, and behaviour. Despite countless advances in neonatal medicine, the incidence of CP has remained constant in term infants over the last three decades. More...
Breathing Dynamics for Non-speech and Speech Tasks Following Intensive Voice and Speech Treatment in Children with Motor Speech Disorders Secondary to Cerebral PalsyDownload
Introduction. Cerebral palsy (CP) is the most frequently occurring cause of movement disorders in children. It has a prevalence of 2-2.5 cases per 1000 live births and is a chronic condition, requiring lifelong rehabilitation. The ability to communicate is a primary factor in positive...
This thesis discusses the organization of motor pathways in adults and children with cerebral palsy (CP). Individuals with CP experience impairments in the control of head and neck functions. The cranial nerves that innervate the head and neck pass through the brainstem. Thus, motor impairment...
Effects of an Intensive Voice Treatment on Articulatory Function and Speech Intelligibility in Children with Motor Speech DisordersDownload
Producing speech that is clear, audible, and intelligible to others is a challenge for many children with cerebral palsy (CP) and children with Down syndrome (DS). Previous studies have demonstrated the effectiveness of using the Lee Silverman Voice Treatment (LSVT LOUD®) to increase vocal...
Hypoxic-ischemic brain damage (HIBD) is still of major concern in the neonatal period, resulting in chronic neurological sequelae stemming from damage to the term newborn brain. Full-body and focal-head cooling within 6 hours of birth have proven neuroprotective in human newborns and various...
Investigating the Role of In Utero Inflammation on Neurodevelopment in the Fetus and Offspring and the Neuroprotective Properties Afforded by Broccoli SproutsDownload
Introduction Maternal infection and inflammation leading to a fetal inflammatory response (FIR) is a risk factor for perinatal brain damage. Perinatal brain injury can lead to neurodevelopmental disorders, the sine quo non outcome parameter of which is cerebral palsy (CP). Despite advances in...
Learning Therapist's Intervention from Demonstration: Application for Robotic Assistance to Children with Cerebral PalsyDownload
Physical interaction with the environment and object manipulation play an important role in the development of children's cognitive and perceptual skills. For children who have severe physical impairments, one of the biggest concerns is the loss of opportunities for play. Robots can be used to...
This thesis discusses the pathophysiological mechanisms underlying neuromotor impairments in people with spastic cerebral palsy (CP). Ninety percent of people with CP have spastic CP and 60% have bilateral motor impairments. The first two chapters introduce CP and review the mechanisms known to...
Cerebral Palsy (CP) constitutes the primary outcome of premature nerve injury. Impairment of oxygen and glucose supply during pregnancy to the fetus can induce neuron damage and death. Mental retardation, seizures, learning disabilities, and other mental diseases can occur as a result of this...