This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
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Spring 2023
As the most metabolically demanding organ in the body, the heart must continually produce extraordinary amounts of energy to sustain constant contractile function. To accommodate for alterations in fuel source availability, the healthy mature heart is omnivorous and possesses the capacity to...
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Fall 2011
The pumping of the heart is controlled at the molecular level by the calcium dependent interaction between troponin C (cTnC) and troponin I (cTnI). The central role this protein-protein interaction plays in the muscle contraction cascade makes it a prime target for the development of drugs for...
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Pathogenesis of Heart and Liver Diseases in Acquired and Genetic Iron-overload Disorders Resveratrol as potential therapy
DownloadFall 2016
Abnormal iron metabolism leads to cardiac and hepatic iron-overload disorders in an epidemic proportion. Irregular iron absorption results in iron deposition in different organs of the body including heart and liver. Iron-overload heart and liver diseases are commonly observed in patients with...
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Role of A Disintegrin and Metalloproteinases (ADAMs)- 15 and 17 in Cardiac Remodelling Following Pressure Overload
DownloadSpring 2024
Myocardial remodeling is a critical process in response to cardiac stress or injury, which includes changes in the cardiomyocyte size, the extracellular matrix (ECM), and cell-ECM interactions. Cardiac hypertrophy is the morphological increase in the myocardial mass by an increase in the...