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Skip to Search Results- 1Asomaning, Justice
- 1Buijs, David, M
- 1Cheng Baron, June
- 1Corscadden, Lisa.
- 1Cyr, Anika
- 1Fillmore, Natasha
- 7Department of Agricultural, Food, and Nutritional Science
- 2Department of Medicine
- 2Department of Oncology
- 2Department of Pharmacology
- 2Department of Physiology
- 1Centre for Neuroscience
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Baker, Kristi (Oncology)
- 1Bressler, David C. (Agricultural, Food and Nutritional Science)
- 1Davidge, Sandra T. (Physiology/Obstetrics and Gynecology)
- 1Dr. David Bressler (Agricultural, Food and Nutritional Science)
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
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Regulation of Anti-tumor Immunity in Colorectal Cancer by Interaction of Exosome Immune Complexes with Fc gamma Receptors
DownloadSpring 2019
Targeted therapy is difficult for colorectal cancer (CRC) due to lack of conserved tumor associated antigens (TAA). Immunotherapies for CRC directed at TAA that can overcome intestinal tolerance need to be developed to improve survival of CRC patients. Exosomes are extracellular vesicles secreted...
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A Novel Comparative Analysis Approach to Personalize Chemotherapy Dose Calculation in Early Breast Cancer
DownloadFall 2018
Background Worldwide, body surface area [BSA] is used to calculate chemotherapy dose. The BSA formula was originally developed in 1916, derived from height and weight, with no consideration of other patient characteristics. Most chemotherapy agents have a narrow therapeutic index and are...
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Spring 2010
Cost-effective processing of dairy whey permeates is important to the environment and economics of the agriculture industry in Canada. Bioconversion of whey permeates is an attractive means of obtaining value-added adjuncts with improved nutritional and functional properties. In the past,...
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Fall 2016
Multiple sources suggest that insulin resistance and derangements of cardiac metabolism are among the earliest signs of type-2 diabetes detected in the heart. Unfortunately, limited evidence reflects early changes in cardiac mitochondrial metabolism linked to the development of this disease....
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Spring 2016
Heart failure is associated with major changes in cardiac energy metabolism that decrease cardiac efficiency, which can reduce cardiac function. In severe heart failure there is a shift back toward a fetal heart metabolism, with a decrease in mitochondrial oxidative metabolism and increase in...
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Fall 2020
Interactions between diet, lifespan, metabolism, and immunity are complex but can have profound impact on human health. The Drosophila model is useful to study these interactions as many pathways and processes are highly conserved between flies and humans. In this thesis, I used the defined...
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Growth of oleaginous yeasts on mixed C5 and C6 sugar streams to generate lipid feedstocks for renewable hydrocarbon production
DownloadSpring 2022
Microbial lipids are a promising feedstock to produce renewable fuels. Lignocellulosic feedstocks can provide multiple carbon sources for microbial growth, such as hexoses (C6) and pentoses (C5). Oleaginous yeasts can convert C5 and C6 sugars to microbial lipids that can be further processed into...