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Skip to Search Results- 53Graduate and Postdoctoral Studies (GPS), Faculty of
- 53Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 4CANHelp Working Group
- 4CANHelp Working Group/Journal Articles (CANHelp Working Group)
- 4Agricultural, Food and Nutritional Science, Department of
- 4Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Systematic microRNAome profiling reveals the roles of microRNAs in milk protein metabolism and quality: Insights on low-quality forage utilization
Download2016
Wang, Diming, Sun, Huizeng, Liu, Jianxin, Guan, Le Luo, Wang, Bing, Liang, Guanxiang
In this study, we investigated the molecular regulatory mechanisms of milk protein production in dairy cows by studying the miRNAomes of five key metabolic tissues involved in protein synthesis and metabolism from dairy cows fed high- and low-quality diets. In total, 340, 338, 337, 330, and 328...
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Spring 2018
Head and neck squamous cell carcinoma (HNSCC) is the 6th most prevalent cancer worldwide with rates of human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) dramatically increasing. The overexpression of enhancer of zeste homolog 2 (EZH2), a histone methyltransferase...
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The effect of eicosapentaenoic and docosahexaenoic fatty acids on body composition and response to chemotherapy in patients with lung cancer
DownloadFall 2011
Patients with lung cancer are at high risk for malnutrition and even mild weight loss has been associated with decreased median survival and poor response to chemotherapy. The purpose of this research was to describe fatty acids status during chemotherapy and determine if supplementation with...
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The Feasibility and Acceptability of a Virtually-Supported Home Exercise Program for People with Multiple Myeloma
DownloadFall 2021
Introduction: Exercise could help alleviate the significant morbidity experienced by people with multiple myeloma (MM). It is unclear if current cancer-specific exercise guidelines are appropriate for this unique population. Supervision, tailoring, and flexibility are proposed as key program...
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The preferred place of last days: Results of a representative population-based public survey.
Download2013
Houttekier, D., Deliens, L., Cohen, J., Hewitt, J. A., Wilson, D. M.
Background: The place of death is of considerable interest now, yet few studies have determined public preferences for place of end-of-life (EOL) care or final days of life. Objective: A survey was designed to answer three questions: (1) What are public preferences for the place of last days?...
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Fall 2014
Chemoresistance is one of the major hurdles to induce a cure in patients with epithelial ovarian cancer (EOC). RUNX3, belonging to the family of RUNX transcription factors, has been shown to act in an oncogenic manner by promoting proliferation and colony formation when overexpressed, in EOC....
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Spring 2015
The tumor suppressor protein Ras association domain family 1A (RASSF1A) has roles in multiple signaling pathways including modulating apoptosis, the cell cycle, DNA damage, and microtubule organization. RASSF1A has been shown to be one of the most frequently epigenetically silenced genes in a...
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Towards superior cancer drugs by modeling approaches: Modification and prediction of the mode of action
DownloadFall 2021
Cancer is a leading cause of death that imposes significant economic and social suffering on a global scale. Based on the projected growth and ageing of populations, the global burden of cancer is set to increase. Despite the vast investment in cancer research, the rate of translation of research...
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Unveiling the pathway for the nuclear translocation of the large mitochondrial enzyme Pyruvate Dehydrogenase Complex (PDC)
DownloadSpring 2021
Pyruvate dehydrogenase complex (PDC) is a mitochondrial enzyme that links glycolysis to oxidative phosphorylation by decarboxylating glucose-derived pyruvate to produce acetyl-CoA that is used in the Krebs cycle. PDC was initially thought to reside only in the mitochondrial matrix but we recently...
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Versatile Polymer-Based Nanomedicines for Drug/Gene Delivery and Cell-based Therapy Applications
DownloadSpring 2021
Advances in polymer science and nanotechnology have allowed the development of biomaterials for cell-based applications, such as the delivery of a variety of drugs and genes, as well as supporting technologies, such as stem cell therapies, tissue engineering and cryopreservation. The progress in...