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Skip to Search Results- 1Abiodun Bello
- 1Bak, Jessi J.
- 1Beggs, Megan R
- 1Bhullar, Harneet
- 1Chow, Patrick Y. T.
- 1Desai, Prajakta V
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Fall 2020
Eukaryotic cells are characterized by the presence of membrane-bound organelles. Close proximity between organelles has been observed for decades, but only recently we have really started to understand the importance of these contacts for cellular function. These contacts consist of areas of...
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Spring 2020
Calcium homeostasis is essential and central to a variety of cellular processes from cell life and death pathways to metabolism to muscle contraction. One component that is essential to intracellular calcium regulation is known as the sarco(endo)plasmic reticulum Ca-ATPase, or SERCA. SERCA...
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Fall 2023
Infants and children require a net positive calcium (Ca2+) balance to achieve optimal bone mineral density by early adulthood. Vitamin D is a hormone that increases blood Ca2+ levels by increasing intestinal absorption and renal reabsorption of Ca2+ as well as bone remodelling. In both the kidney...
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Modulation of Spontaneous Neural Network Bursting in Newborn Rat Brain Slices by Extracellular Calcium, Methylxanthines, and Opioids
DownloadFall 2012
Spontaneous neuronal bursting appears to be pivotal for brain maturation. This thesis studied such synchronized neural network oscillations in immature newborn rat hippocampus, cortex, and locus coeruleus. For this, horizontal brain slices were generated for (simultaneous) suction electrode...
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Spring 2022
Alzheimer’s Disease (AD) is an insidious, progressive neurodegenerative disease responsible for the majority of dementia cases worldwide. Despite extensive research and clinical trials, there are currently no approved treatments that alter the progression of the disease. Treating classic...